Welcome Message
We cordially invite you to attend the next Symposium on Alzheimer's Disease (2nd AD Symposium). After the success of the 1st edition (online), which had over 400 participants, the 2nd Symposium on Alzheimer's Disease will attract international scientists and young students from all over the world. The AD Symposium continues to be at the vanguard of understanding the mechanisms and improving the therapy of Alzheimer’s disease. The next AD Symposium in 2023 will be held in the charming city of Porto, Portugal, from February 10-11, 2023.
This is a Hybrid Symposium, so if it is difficult for you to attend onsite, virtual presentations will also be available by zoom.
On the first day of the event, several oral and poster presentations will take place, which will allow the presentation and discussion of recent scientific progress. On the second day, there will be a workshop on the manufacture and characterization of nanoparticles, providing the opportunity to learn about innovative nanoparticle production and characterization methods, biocompatible materials, commercial nanoparticles, and their current trends in the market. There will be an engaging round table to wrap up the session.
The best oral presentation and poster will be awarded.
Abstract Submission
Abstract Submission for oral presentations closed on January 25th, 2023.
Abstract Submission for poster communications closed on January 31st, 2023.
Instructions to Authors:
Each participant may present a maximum of 1 poster or oral presentation.
The presenting author is required to ensure that all co-authors are aware of the content of the abstract before submission.
All abstracts should be submitted and presented in clear English with accurate grammar and spelling.
All abstracts accepted for presentation will be published on the website prior to Symposium.
Please note that the submitting author will receive all correspondence about the abstract.
An e-mail confirming the successful abstract submission will be sent within 24h. If you do not receive the email, please contact us.
Scientific Program
February 10th, 2023
9:15
Registration
9:45
Opening Session
Maria do Carmo Pereira | LEPABE, Faculty of Engineering, University of Porto, Portugal
Chair
Hélio Albuquerque | University of Aveiro, Portugal
10:00
Blood-brain barrier in Alzheimer's disease and in CNS drug delivery
Fabien Gosselet | Artois University, France
Invited Speaker
10:30
Mechanisms of aging in Health and Neurodegenerative Disorders as revealed by brain imaging approaches
Miguel Castelo Branco | University of Coimbra, Portugal
Invited Speaker
11:00
Early diagnosis of Alzheimer's disease using MRI: a machine-learning approach
Vasco Sá Diogo | University of Lisbon, Portugal
11:15 - 11:30
Coffee break
Chair
Mónica Almeida Vieira | School of Health Sciences - Polytechnic of Porto, Portugal
11:30
Tau aggregates in dementia. Role in risk, disease and therapy
Ines Moreno Gonzalez | University of Malaga, Spain
Invited Speaker
12:00
Involvement of the PI3K/AKT Pathway in the Mechanism of Angiotensin I Receptor Blockers Against Cognitive Decline
Filipa Gouveia | University of Coimbra, Portugal
12:15
Explore novel compounds to prevent TrkB-FL cleavage
Sara Inteiro-Oliveira | University of Lisbon, Portugal
12:30 - 14:00
Poster Session / Lunch*
Chair
Odete da Cruz e Silva | University of Aveiro, Portugal
14:00
Exosomes and Alzheimer’s disease in the novel era of Precision Medicine
John-Ioannis Sotiropoulos | IBA, NCSR Demokritos, Greece & ICVS, University of Minho, Portugal
Invited Speaker
14:30
The late-onset Alzheimer's disease risk factor CD2AP may impact synapses independently of beta-amyloid
Cláudia Guimas Almeida | NOVA Medical School, NOVA University Lisbon, Portugal
Invited Speaker
15:00
Analyzing Neuroimmune-associated miRNA dysregulation in Alzheimer´s disease
Gonçalo Garcia | University of Lisbon, Portugal
15:15
The role of tau in the regulation of translational stress response and its importance for brain pathology
Joana Silva | University of Minho, Portugal
15:30 - 16:00
Coffee break
Chair
João Bettencourt Relvas | i3S, Portugal
16:00
RNA biopharmaceuticals: from recombinant production to the cellular application – The case study of miRNAs for Alzheimer’s disease
Fani Sousa | University Beira Interior, Portugal
Invited Speaker
16:30
Beating the blood-brain barrier to target Alzheimer's and other brain diseases
Miguel Castanho | Institute of Molecular Medicine, Faculty of Medicine, University of Lisbon, Portugal
Invited Speaker
17:00
Studies on the role of Transthyretin in amyloid-β peptide elimination: Impact on the expression of amyloid-β transporters at the BCSFB
Tiago Gião | University of Porto, Portugal
17:15
Detection of amyloid-beta oligomers in early Alzheimer´s disease
Alexandre Lima | University of Minho, Portugal
17:30
Influence of materials and process parameters on the development of lipid nanoparticles formulations for nose-to-brain drug delivery
Carmo Correia | University of Porto, Portugal
17:45
Walking city tour (optional)
February 11th, 2023
9:30 - 12:30
Workshop on Nanoparticle Production and Characterization for Biomedical Applications
12:30 - 14:00
Lunch*
14:00 - 15:30
Round Table
Chair: Maria do Carmo Pereira | LEPABE, Faculty of Engineering, University of Porto, Portugal
Ana Catarina Silva | University Fernando Pessoa, Portugal | UCIBIO, Faculty of Pharmacy, University of Porto, Portugal
Bárbara Gomes | CEO of AccelBio's, Portugal
Paula Sampaio | CSO of iLof, Portugal
Luísa Alves | Neurologist, Egas Moniz Hospital - West Lisbon Hospital Center, Portugal
15:30
Closing Session and Awards Ceremony
Joana A. Loureiro | LEPABE, Faculty of Engineering, University of Porto, Portugal
* There are several restaurants available at FEUP's facilities
Workshop
Nanoparticle Production and Characterization for Biomedical Applications
Learn from experts in the field of nanotechnology for Alzheimer’s disease and related dementias. This immersive learning experience, which is intended for students, postdoctoral fellows, and other early-career scientists, will increase your knowledge, expertise, and visibility in this fascinating topic. The workshop on nanoparticle manufacturing and characterization will give participants a chance to learn new things about biocompatible materials, nanoparticles currently on the market, and other topics.
The workshop will be held on Saturday, February 11th, 2023, at FEUP. A limited number of participants will be selected in order to ensure an interactive and engaging workshop experience.
Invited Speakers
Cláudia Guimas Almeida
NOVA Medical School, NOVA University, Portugal
Fabien Gosselet
Artois University, France
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Fani Sousa
University Beira Interior, Portugal
Ines Moreno Gonzalez
University of Malaga, Spain
John-Ioannis Sotiropoulos
IBA, NCSR Demokritos, Greece & ICVS, University of Minho, Portugal
Miguel Castanho
IMM, Faculty of Medicine, University of Lisbon, Portugal
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Miguel Castelo Branco
University of Coimbra, Portugal
Venue
The 2nd symposium on AD will be held at the Faculty of Engineering of the University of Porto (FEUP)
Rua Dr. Roberto Frias, s/n 4200-465 Porto, Portugal
Coordinates: 41.1780, -8.5980 (41º 10’ 40.8’’ N, 8º 35’ 52.8’’ W)
Travel information
By plane (Francisco Sá Carneiro Airport): The quickest way of getting to FEUP from the airport (if you do not have transport waiting for you or do not intend to catch a taxi) is to take Metro Line E (purple) into Porto. You will need to change at Trindade station and take Line D (yellow). Then follow the directions given in the option “By Metro”.
By train: If you are coming to Porto by train, there are two main ways to the Faculty, depending on which station you arrive at: If you are arriving from Campanhã station, you should catch the Metro and choose any one of the following lines: A (blue), B (red), C (green) or E (purple). You will have to change at Trindade station to catch Line D (yellow). You should then follow the directions given in the option “By Metro”. If you are arriving from S. Bento station, you should take Metro Line D (yellow) and then follow the directions given in the option “By Metro”.
By bus: There are 4 bus lines in the Faculty’s zone: 204, 300, 301, and 803. There are other STCP bus lines from Hospital de S.João, as well as regular bus routes to other cities.
By metro: FEUP is served by three Metro stations on line D (yellow) in zone C6.
Line D connects the University Campus station Polo Universitário to Gaia City Hall in about 15 minutes, via Trindade, where it connects to line A (blue), line B (red), and line C (green). Leaving the Polo Universitário station, you should turn left into Rua Dr. Manuel Pereira da Silva and then, after passing Paranhos cemetery, turn left into Rua Dr. Roberto Frias. Go straight on, and you will find FEUP on your right.
Leaving the IPO station, you should go on down to the end of Rua Dr. Plácido da Costa and cross Rua Dr. Roberto Frias. You will then be in front of FEUP.
Leaving the Hospital de São João station, follow the Circunvalação ring road until you come to the junction with Rua Dr. Roberto Frias. Go down that road until the junction with Rua Dr. Plácido da Costa. FEUP will now be on your left.
Accommodation
Near to FEUP
HOTEL IBIS SÃO JOÃO **
Rua Dr. Plácido Costa | 4200-450 Porto
Telephone: (+351) 225 513 100
E-mail: h3227@accor.com
EUROSTARS OPORTO HOTEL ****
Rua do Mestre Guilherme Camarinha, 212 | 4200-537 Porto
Phone: (+351) 225 072 090
E-mail: reservas@eurostarsoporto.com
AXIS PORTO – BUSINESS & SPA HOTEL ****
Rua Maria Feliciana, 100 – São Mamede de Infesta | 4465-283 Matosinhos – Porto
Phone: (+351) 229 052 000
E-mail: reservas@axisporto.com
Near downtown Porto
HOTEL MOON & SUN PORTO ****
Rua Sá de Noronha, 70, Porto, Porto 4050-526 Portugal
Phone: (+351) 222 081 875
E-mail: geral@ms-hotels.com
PORTO TRINDADE HOTEL ****
Rua de Camões, nº 129 / 131 | 4000-144 Porto
Telephone: (+351) 222 061 520
E-mail: geral@portotrindadehotel.com
HOTEL PORTO MOOV CENTRO **
Praça da Batalha 32, 4000-101 Porto
Telephone: (+351) 220 407 000
E-mail: porto@hotelmoov.com
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Contact us
Sponsors
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This event was financially supported by LA/P/0045/2020 (ALiCE), UIDB/00511/2020, and UIDP/00511/2020 (LEPABE), funded by national funds through FCT/MCTES (PIDDAC); Project 2SMART - engineered Smart materials for Smart citizens, with reference NORTE-01-0145-FEDER-000054, supported by Norte Portugal Regional Operational Program (NORTE 2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF); National funds through the FCT/MCTES (PIDDAC) under the project EXPL/NAN-MAT/0209/2021; European Union’s Horizon 2020 research and innovation programme under grant agreement No 958174; National funds through FCT (M-ERA-NET3/0001/2021); Prize Maratona da Saúde for Cancer Research; and Santa Casa da Misericórdia (MB-35-2021). FCT supported S.A. (EXPL/NAN-MAT/0209/2021), D.N. (UI/BD/150946/2021), M.D. (SFRH/BD/040932/2020), and M.J.R. under the Scientific Employment Stimulus - Individual Call – (CEEC-IND/01741/2021).
